How Much Does Mosquito Treatment Cost in Charleston?

Last updated: May 21, 2026

By Pest Control Pricing Team

Mosquito treatment in Charleston, SC costs $65 to $110 per visit for a typical quarter- to half-acre residential lot, with most homeowners spending $450 to $750 for a seven-visit seasonal program running April through October. Charleston's combination of salt marsh, tidal creeks, freshwater wetlands, dense ornamental landscaping, and a nine-month active season makes the Lowcountry one of the highest-pressure mosquito environments on the East Coast, with at least 33 native species producing year-round breeding in mild winters.

What does mosquito treatment cost in Charleston?

Charleston mosquito treatment pricing depends on three factors: yard size, treatment frequency, and whether you bundle additional services. The peninsula, West Ashley, James Island, Mount Pleasant, Daniel Island, and the surrounding Charleston County footprint all fall within similar pricing bands, with island and Kiawah / Seabrook properties trending slightly higher due to travel time and stricter buffer requirements near tidal water.

A standard residential barrier spray on a quarter-acre to half-acre lot costs $65 to $110 per visit. The technician uses a backpack mister to apply a pyrethroid-based residual product (commonly bifenthrin or lambda-cyhalothrin) to shaded vegetation, the underside of decks and crawl spaces, fence lines, and resting sites in low ornamentals like liriope, azaleas, gardenias, and Japanese hollies. Treatment takes 30 to 60 minutes, residual control lasts three to four weeks, and yard access is restored within 30 minutes to an hour after spraying.

Larger properties price by acreage. Half-acre to three-quarter-acre lots common in older Mount Pleasant, James Island, and Johns Island neighborhoods run $95 to $145 per visit. Estate-scale properties on Kiawah, Daniel Island, Wadmalaw, or Edisto pay $145 to $225 per visit, with $300+ pricing for multi-acre properties requiring truck-mounted equipment.

Charleston pricing sits modestly above the national median for mosquito treatment because of the extended season and the buffer protocols required near tidal water. For comparison with other Southeast cities on our network, see mosquito treatment cost in Atlanta, Tampa mosquito treatment cost, and the national mosquito treatment cost guide for baseline ranges. Charleston runs $5 to $20 per visit higher than Atlanta on equivalent lot sizes due to longer travel between properties on the islands and the shorter daily treatment window during summer afternoon thunderstorms.

Why Charleston has such high mosquito pressure

Charleston's mosquito problem is not one problem, it is at least three overlapping problems, driven by different species using different breeding habitat. Understanding which species is biting you helps explain why barrier spraying works against some Charleston mosquito complaints and not others, and why source reduction matters more here than in drier climates.

Salt marsh mosquitoes (Aedes sollicitans, Aedes taeniorhynchus)

Salt marsh mosquitoes are the species that produces the massive emergences after spring tides and tropical rainfall, the kind that turn a Mount Pleasant or Sullivan's Island porch unusable within two days of a coastal flooding event. Females lay eggs on damp salt marsh mud above the normal high tide line. The eggs can lie dormant for months, then hatch all at once when an unusually high tide (a king tide, a spring tide, or storm surge) floods the egg-laying zone. A single tidal flood event in the ACE Basin or the marshes around the Wando River can produce broods in the tens of millions.

These mosquitoes can fly 10 to 20 miles from their breeding sites, which is why salt marsh emergences hit Daniel Island, downtown, and even inland West Ashley simultaneously. Salt marsh mosquito populations are what Charleston County Mosquito Control monitors most aggressively, because they are the species driving most of the County's truck-fogging and aerial treatment decisions. Barrier sprays on your own yard reduce the resting adults that land in your shrub line, but during a major emergence the re-invasion pressure overwhelms typical residential treatment for several days. This is the period when even properties on a seasonal program need a supplemental between-visit re-treatment.

Container-breeding Aedes (Aedes aegypti, Aedes albopictus)

The Asian tiger mosquito (Aedes albopictus) and yellow fever mosquito (Aedes aegypti) breed in container water on your own property. They lay eggs on the inside walls of any container that holds water for more than a week: plant saucers, bird baths, French drains, tarps, kid toys, clogged gutters, bromeliads, abandoned tires, AC condensate trays, even the folds of a pool cover. Eggs hatch in days when re-flooded by rain. These species are active during the day, especially morning and late afternoon, and account for the majority of "the mosquitoes are biting me in my own backyard" complaints in Charleston neighborhoods like Wagener Terrace, North Central, Hampton Park, Avondale, and Old Mount Pleasant.

Female Aedes albopictus only fly 200 to 300 feet from where they emerged, so the container breeding happening within a block of your home drives most of your bites. Barrier spraying knocks down resting adults, but unless container water is eliminated, new adults emerge every 7 to 14 days. This is why source reduction (dumping standing water weekly, treating French drains with Bti, fixing gutter clogs) is more effective than spraying for container breeders.

Freshwater Culex species (Culex quinquefasciatus, Culex nigripalpus)

Culex mosquitoes breed in stagnant freshwater, storm drains, retention ponds, neglected pools, drainage ditches in West Ashley and Johns Island, and the freshwater impoundments around Magnolia Gardens. They feed at dusk and dawn and rest in shrubs and tall grass. Culex species are the primary vectors of West Nile virus and Eastern Equine Encephalitis (EEE) in South Carolina. SCDHEC tracks Culex populations as part of arbovirus surveillance, and confirmed human cases in Charleston County, while rare, do occur most years.

Charleston neighborhood pressure: where mosquitoes are worst

Mosquito pressure varies dramatically across the Charleston metro. Two neighborhoods five miles apart can experience completely different biting intensity based on proximity to marsh edge, freshwater wetland density, tree canopy, and the age and drainage condition of the housing stock.

The pattern: anywhere within a mile of salt marsh experiences salt marsh mosquito broods during spring tides and storm-driven flooding (May through October peaks). Anywhere with mature tree canopy and dense ornamental landscaping (essentially every Charleston neighborhood with houses over 30 years old) experiences container-breeder pressure all season. The downtown peninsula south of Calhoun has the lowest pressure in the metro because of sea breeze, less landscaping per square foot, and limited freshwater retention.

What methods do Charleston pest control companies use?

Effective Charleston mosquito control combines four mechanisms. Reputable pest control operators use multiple methods rather than relying on barrier spraying alone, because no single method addresses all three of Charleston's mosquito problems (salt marsh, container, Culex) simultaneously.

Pyrethroid barrier sprays

The workhorse of professional mosquito control. Pyrethroid products (bifenthrin, lambda-cyhalothrin, deltamethrin, permethrin) are applied with a backpack mister to foliage where adult mosquitoes rest during the day: the underside of leaves on liriope, azaleas, hydrangeas, gardenias, and Japanese hollies; the lower 6 to 8 feet of ornamental trees; the underside of decks and the framing of crawl spaces. Pyrethroids work because they bind tightly to the plant cuticle (the waxy outer layer of leaves) and remain biologically active against landing mosquitoes for three to four weeks. The active ingredient breaks down in sunlight and washes off in heavy rain, which is why summer thunderstorm activity occasionally requires an early re-treatment.

Pyrethroids are not toxic to mammals at the concentrations applied, but they are highly toxic to fish, shrimp, and other aquatic invertebrates. South Carolina DPR rules and EPA label requirements prohibit application within ten feet of standing water that drains to tidal creeks. In Charleston, where many properties drain directly to creek systems feeding the Ashley, Cooper, Wando, and Stono Rivers, technicians must visually identify drainage paths and adjust treatment zones accordingly. A Charleston technician who sprays right up to the marsh edge is violating both the product label and SCDPR regulations.

Larviciding (source reduction with Bti)

Bacillus thuringiensis israelensis (Bti) is a naturally occurring soil bacterium that produces a toxin lethal to mosquito and black fly larvae but harmless to virtually everything else. Bti is sold commercially as Mosquito Dunks (slow-release briquettes) and Mosquito Bits (granules). Charleston County Mosquito Control uses Bti to treat catch basins, drainage ditches, and standing water on County land. A professional residential treatment program should include Bti placement in any standing water that cannot be eliminated: French drain catch basins, ornamental ponds without fish, bromeliad cups, rain barrels, and pool covers. Bti is the single most effective treatment for container-breeding Aedes when source elimination is not possible.

In2Care stations and bait-based programs

In2Care is a newer technology gaining traction in Charleston. The stations are small black cylinders placed every 100 to 200 feet around your property, each containing water treated with a larvicide and a fungal pathogen. Female Aedes mosquitoes lay eggs in the station, get contaminated, then carry the contamination back to natural breeding sites where it kills both larvae and the female. The net effect is suppression of the local Aedes population over 6 to 8 weeks. In2Care programs cost more than standard barrier programs ($550 to $1,100 per season) but address container-breeding species more directly. They pair well with barrier spraying for properties with persistent Aedes albopictus problems.

Misting systems

Permanent perimeter tubing with timed nozzles, releasing pyrethrin or pyrethroid concentrate twice daily. Misting systems work, especially on properties that entertain frequently or back up to marsh. Installation runs $2,000 to $4,500 with seasonal refills of $300 to $600. The trade-offs: continuous low-dose application is less effective per ounce of product than spot-applied barrier sprays, the systems require maintenance, and Charleston County restricts misting system installation on properties draining directly to tidal water in some zones. Verify with your applicator and with Charleston County before signing an installation contract.

Natural and botanical treatments

Cedar oil, garlic, geraniol, and rosemary-extract products are sold as "natural" or "organic" mosquito treatments. They work, but with shorter residual (typically 7 to 14 days versus 21 to 28 days for pyrethroids) and higher per-visit cost. Natural treatments are appropriate for properties near aquatic habitat where pyrethroid use is restricted, for households with extreme pesticide sensitivity, or for homeowners who want to keep pollinator-friendly plantings. Expect to pay $75 to $145 per visit and accept more frequent re-treatment.

What homeowners must do for treatment to work

Professional mosquito treatment in Charleston is half the equation. The other half is source reduction, and no amount of barrier spraying compensates for an unaddressed breeding site on your property. The Centers for Disease Control's container-survey methodology (counting every potential breeding site within 100 feet of a structure) routinely finds 15 to 50 container breeding sites in Charleston yards on initial inspection. Eliminating these is more impactful than any chemical treatment.

Walk your property weekly during mosquito season and dump every container holding water. This includes plant saucers, kid toys, buckets, wheelbarrows, tarps, recycling bins left uncovered, anything that catches water from a thunderstorm. Empty bird baths and refill weekly. Replace water in dog bowls daily. Cover or invert anything that can hold water when not in use.

Clear gutters in spring and fall. A clogged section of gutter holds water for weeks and produces hundreds of mosquitoes per linear foot. Gutter cleaning is one of the highest-impact preventive measures and one of the most overlooked.

Treat French drains with Bti monthly during the active season. Most Charleston yards with French drains have larvae breeding in the catch basins between rain events. Drop one or two Mosquito Dunks into each catch basin every 30 days. The dunks dissolve slowly and are effective whether or not the basin currently holds water (they activate when re-flooded).

Check bromeliads, banana trees, and other plants that hold water in leaf axils. Container Aedes will breed in tablespoons of water. Flush bromeliad cups with a hose weekly.

Fix or report standing water you cannot address yourself. Storm drains holding water for more than a few days are a Charleston County Mosquito Control issue (843-202-7880). Neighbor's neglected pool? Call SCDHEC. Abandoned property with junk in the yard? The City of Charleston Livability and Tourism office handles abandoned-property nuisance complaints.

How to choose a Charleston mosquito treatment company

Charleston has roughly 40 to 60 active residential pest control companies offering mosquito treatment, ranging from solo operators to regional chains to national brands like TruGreen, Mosquito Joe, and Mosquito Authority. Selection criteria that matter in Charleston specifically:

Confirm South Carolina DPR licensing in category 7B. The South Carolina Department of Pesticide Regulation at Clemson University licenses all commercial pesticide applicators in the state. Residential mosquito work requires category 7B (Industrial, Institutional, Structural, and Health Related Pest Control). Ask for the license number and verify it through the SCDPR online lookup. Unlicensed mosquito treatment is illegal under South Carolina Pesticide Control Act regulations and any property damage or injury claims against an unlicensed applicator are uninsurable.

Ask about tidal water buffer protocols. A Charleston applicator who works near marsh should be able to explain their buffer practice without hesitation: ten feet minimum from standing water that drains to tidal systems, no application when wind exceeds 10 mph, no pre-storm application. If the rep cannot answer this question, find another company.

Verify general liability insurance. A minimum of $1 million general liability is standard for residential pest control in Charleston. The certificate of insurance should list your property as a covered location during the work. Pesticide application creates rare but real damage risk (ornamental plant damage from over-application, pet exposure, accidental drift onto a neighbor's pollinator garden) that you want covered.

Get written re-treatment policy. A reputable Charleston mosquito company offers free re-treatment between scheduled visits if mosquito activity returns within the residual window (typically 14 to 21 days into the 28-day cycle). Companies that charge for re-treatments are pricing the program too low and making up the gap on call-backs.

Check Better Business Bureau and Google reviews for the local branch, not the national brand. National-chain Charleston franchises sometimes operate differently than the brand's national reputation suggests. A 4.7-star national rating means little if the Charleston franchisee has 3.2 stars locally.

Ask which products they use. "We use what's safe" is not an answer. A real answer names the active ingredient and the formulation: "We use bifenthrin in a microencapsulated formulation for residual barrier, supplemented with Bti briquettes in any standing water." The willingness to specify products correlates strongly with applicator skill.

Avoid companies that promise guarantees on mosquito-borne illness prevention. No mosquito treatment eliminates 100 percent of mosquitoes, and any company promising that you cannot get West Nile, EEE, or Zika because of their treatment is misrepresenting the product. The honest framing: barrier spraying reduces adult mosquito activity by 80 to 90 percent in treated zones for 3 to 4 weeks, which substantially reduces (but does not eliminate) exposure risk.

How Charleston compares to other Southeast cities

Charleston mosquito pressure and treatment costs land in the middle of the Southeast market. The closest comparable cities (in terms of mosquito species mix, season length, and pricing) are Savannah, Wilmington NC, and Jacksonville. Cities with more aggressive municipal mosquito control programs (notably parts of metropolitan Atlanta) experience modestly lower private treatment demand because the County and City handle more of the public-land breeding sources.

For pricing comparison, see mosquito treatment cost in Orlando and Houston mosquito treatment pricing, both of which run similar season-long programs in the $450 to $800 range. Nashville mosquito treatment tends to run lower ($350 to $600 seasonal) because of a shorter active season. Dallas mosquito treatment runs comparably to Charleston but with less salt-marsh pressure and more freshwater Culex activity.

Within South Carolina specifically, Charleston pricing sits roughly $10 to $25 per visit above inland markets like Columbia and Greenville due to longer drive times, island accessibility constraints, and the buffer protocols required near tidal water. For comparison with other Lowcountry pest pressures specific to Charleston, see the Charleston pest control cost guide, the Charleston mosquito problem overview, and termite inspection in Charleston, which covers the related subterranean termite pressure driven by the same humidity and tidal water table that produces mosquito breeding habitat.

Mosquito-borne disease risk in Charleston

The South Carolina Department of Health and Environmental Control (SCDHEC) tracks mosquito-borne disease across the state. Charleston County reports a handful of human West Nile virus cases most years, occasional Eastern Equine Encephalitis (EEE) cases (rare but more serious), and sporadic locally-acquired dengue, Zika, or chikungunya cases tied to travel-imported introductions. Heartworm in dogs is significantly more common than human arboviral disease, your veterinarian's heartworm prevention recommendation is medically grounded in Charleston's mosquito ecology.

The species mix matters. Culex quinquefasciatus and Culex nigripalpus are the primary West Nile vectors. Aedes albopictus can transmit chikungunya, dengue, and Zika when introduced into a population. Aedes aegypti, which has been re-establishing in parts of the Southeast as climate warms, is the most efficient vector for the same diseases. Charleston has historically had limited Aedes aegypti presence, but SCDHEC and Charleston County Mosquito Control track its expansion. Reducing adult mosquito populations through professional treatment and source reduction reduces exposure risk, though no treatment program eliminates disease transmission risk entirely.

For disease surveillance information and to report unusual mosquito activity or suspected disease transmission, SCDHEC maintains a public arbovirus surveillance dashboard updated weekly during active season. Charleston residents experiencing sudden high fever, severe headache, neck stiffness, or confusion during peak mosquito season should mention mosquito exposure to their physician and consider testing for West Nile and EEE.

Treatment is preventive. Active illness is a medical matter, not a pest control matter.

Response time and scheduling in Charleston

The South Carolina Lowcountry network of mosquito control providers that we refer to operates on an independent contractor basis. Response times depend on local conditions, current call volume, and weather. During peak season (May through September) and especially in the days following tropical storms or major coastal flooding events, response times extend as demand spikes. We cannot guarantee any specific response window in Charleston. What we can do is connect you to a licensed Charleston-area mosquito treatment professional quickly, typically within one business day during normal operations.

About referrals and your call

We are an information and referral service for Charleston residents looking for licensed mosquito treatment. We are not the company that comes to your property and applies treatment. When you call (000) 000-0000, you are connected to a licensed South Carolina pest control provider in our Charleston network who handles your treatment, pricing, and scheduling directly. Pricing in this guide reflects typical Charleston-area market ranges and is provided for planning purposes. The provider quotes your specific property after inspection. We may receive a referral fee from the network provider. This does not affect what you pay.

Charleston mosquito treatment FAQ

How much does professional mosquito treatment cost in Charleston?

A standard residential mosquito treatment in Charleston runs $65 to $110 per visit for a quarter-acre to half-acre lot, with most homeowners on a seven-treatment seasonal program paying $450 to $750 for the full April-through-October coverage. Larger Mount Pleasant or Daniel Island lots (three quarters of an acre and up) push per-visit pricing to $125 to $185. One-time event sprays for weddings or oyster roasts cost $125 to $250 depending on yard size and how far in advance you book.

Does Charleston County or the City of Charleston spray for mosquitoes?

Yes. Charleston County Mosquito Control runs an integrated program with truck-based ULV (ultra-low volume) fogging, aerial spraying in heavy-pressure marsh corridors, and larviciding of standing water on public land. Residents can request service or report a problem by calling 843-202-7880 or filing a complaint through the County's online portal. County trucks typically run after dusk when adult mosquitoes are active. The City of Charleston coordinates with County operations rather than running a separate spray program. County treatment is free and useful, but it covers public rights-of-way and standing-water sources on County-managed land. It does not treat your private yard, your shrub line, or the underside of your raised foundation, which is where Charleston's two biggest backyard biters (Aedes aegypti and Aedes albopictus) actually rest during the day.

Are professional mosquito treatments actually worth it in the Lowcountry?

For most Charleston homeowners with outdoor space they want to use between May and October, yes. The Lowcountry has roughly 33 native mosquito species, a nine-month active season, and habitat (salt marsh, freshwater wetlands, tidal creeks, dense ornamental landscaping) that produces continuous breeding pressure. A barrier treatment reduces adult mosquito activity in the treated zone by 80 to 90 percent for three to four weeks. The trade-off is cost ($450 to $750 per season) and the need for repeat applications. Treatment is less worth it for renters in second-floor units with no yard, homeowners who rarely use outdoor space, or properties immediately adjacent to large undeveloped marsh where re-invasion is constant.

What is a mosquito's worst enemy in the Charleston area?

Standing water elimination is the single most effective mosquito control method, more effective than any spray. Female mosquitoes need standing water to lay eggs, and the container-breeding species that drive most backyard biting in Charleston (Aedes aegypti, Aedes albopictus) breed in water sources as small as a bottle cap. Dragonflies, Gambusia mosquitofish (used in ornamental ponds), and Bacillus thuringiensis israelensis (Bti, a biological larvicide sold as Mosquito Dunks) are the most effective natural and biological predators. Bti is what County Mosquito Control uses in catch basins and ditches. For your yard, dumping standing water weekly, treating French drains and bromeliads with Bti, and clearing gutters does more than spraying.

How much does TruGreen mosquito treatment cost in Charleston compared to local pest control companies?

TruGreen's mosquito defense program in Charleston is typically priced at $60 to $90 per visit on a seasonal contract, comparable to local pest control companies. Local Charleston-area pest companies often price slightly higher per visit but include broader pest coverage (palmetto bugs, ants, spiders) in bundled plans. National chains tend to push add-on tick treatment as a separate line item, where some local companies fold it in. The real difference is usually scheduling responsiveness and re-treatment policy, local operators tend to honor between-visit re-sprays faster, while national chains route through a call center.

When does mosquito season start and end in Charleston?

Mosquito activity in Charleston starts in late March and runs through November in a typical year, with peak biting pressure from June through September. Salt marsh mosquitoes (Aedes sollicitans, Aedes taeniorhynchus) emerge in massive broods after spring tides and tropical rainfall. Container breeders peak in July and August when summer thunderstorms fill every catch basin and abandoned plant saucer. Mild winters extend activity, in years when Charleston stays above 50 degrees through December, container species can produce broods year-round. Most professional treatment programs run March or April through October, with seven monthly visits.

Do mosquito treatments work on the Asian tiger mosquito (Aedes albopictus)?

Yes, but the Asian tiger mosquito is harder to control than salt marsh species because it breeds in container water on your own property and rests in low, dense ornamental shrubs. Barrier treatments using pyrethroids (bifenthrin, lambda-cyhalothrin) applied to liriope, azaleas, hollies, and the underside of decks knock down resting adults effectively. But because females only fly 200 to 300 feet from where they emerged, any untreated standing water on your property continues producing new adults within days. Asian tiger mosquito control in Charleston requires both barrier spraying and active source reduction, treatment alone leaves you frustrated.

Is mosquito treatment safe for kids, dogs, and shrimp creek?

Pyrethroid barrier sprays (the standard treatment) bind tightly to foliage and soil and have low mammalian toxicity once dry, typically within 30 minutes to an hour. Reputable Charleston applicators will not spray when wind exceeds 10 mph, will skip flowering plants where pollinators are active, and will not treat within ten feet of standing water that drains to tidal creeks. Pyrethroids are highly toxic to fish and crustaceans, so applicators working in West Ashley, James Island, and Mount Pleasant near shrimp creeks must use buffer zones and avoid pre-storm applications. Confirm your applicator is South Carolina DPR-licensed (Department of Pesticide Regulation) and ask about their buffer protocol before signing a contract.

What's the difference between barrier spraying and a misting system in Charleston?

Barrier spraying is a technician applying liquid pesticide every three to four weeks using a backpack mister or truck-mounted sprayer ($65 to $110 per visit). A misting system is permanent tubing installed around your property perimeter that releases timed bursts of pyrethrin or pyrethroid concentrate twice a day. Misting system installation in Charleston costs $2,000 to $4,500 for a typical residential perimeter with refills running $300 to $600 per season. Misting systems suit large properties with frequent outdoor entertaining (Kiawah, Daniel Island estates, downtown courtyards) where the convenience outweighs the cost. They are not allowed on properties draining directly to marsh in some Charleston County zones.

Why are mosquitoes worse on James Island and Johns Island than downtown Charleston?

James Island, Johns Island, and the Wadmalaw / Edisto corridor have more undeveloped land, more freshwater wetlands, and longer marsh edges than the Charleston peninsula. Salt marsh mosquito broods (Aedes taeniorhynchus) can travel 10 to 20 miles from their breeding sites, but pressure is highest within a mile of the marsh. Downtown Charleston south of Calhoun has fewer breeding sites within flight range, more impervious surfaces, and steadier sea breeze that disperses adults. Mount Pleasant's Old Village and Sullivan's Island sit between, with high pressure during salt marsh emergences but lower container-breeder load than wooded inland neighborhoods.

Do mosquito treatments also kill no-see-ums and biting midges?

Partially. The no-see-ums (Culicoides biting midges) that torment Charleston residents at dawn and dusk from May through October are not affected by the same residual barrier sprays that knock down mosquitoes. Pyrethroid barriers reduce adult midges briefly during the active treatment window but do not provide three- to four-week residual control because midges breed in tidal mud, not in your yard. Most Charleston mosquito programs include a no-see-um disclaimer in their contracts. Effective midge control on barrier islands requires different products (sometimes a separate ULV fog) and a separate price.

How fast can a Charleston mosquito treatment company come out before an event?

Most established Charleston companies can schedule an event spray within three to seven days during the regular season, dropping to one to three days for existing customers. For weddings at Boone Hall, Magnolia Plantation, or backyard events on Sullivan's Island, schedule at least two weeks ahead during peak May-through-October booking. Same-day or next-day event sprays exist but cost a premium ($175 to $300). Treatment should be applied 24 to 48 hours before the event for maximum residual on foliage. Spraying the morning of an event reduces immediate adult population but does not deliver full residual coverage.

Do I need a license to spray for mosquitoes on my own Charleston property?

A homeowner spraying their own property with consumer-grade products from a hardware store does not need a license. A contractor or property manager spraying someone else's property in South Carolina must hold a Commercial Pesticide Applicator license issued by the South Carolina Department of Pesticide Regulation at Clemson, with category 7B (Industrial, Institutional, Structural, and Health Related Pest Control) for residential mosquito work. Verify any company you hire is licensed by checking the SCDPR public license lookup or asking for their license number. Unlicensed mosquito spraying is illegal and uninsured.